25-year-old patient in the morning on an empty stomach took blood serum for analysis, after storing it in the refrigerator for 16 - 24 hours white fatty flakes appear above the transparent serum. The blood levels of triglycerides are sharply elevated, the concentration of cholesterol is slightly elevated. There are no clinical signs of atherosclerosis. Marked by the presence of xanthomas
What is the preliminary diagnosis? HYPERLIPIDEMIA TYPE 1ST
What enzyme deficiency is observed in this
case? LIPPOPROTEIN LYPES
What types of lipoproteins do you know?HDL, LDL, IDL, VLDL,
CHYLOMICRONES
Chylomicrons. Structure. Synthesis.
Functions. B48 APPOPROTEIN
, SYNTHESIS
IN INTESTINE, FUNCTION IS TRANSPRTATION OF LIPID TO PERIPHERAL
TISSUE
VLDL, IDL, LDL. Structure. Synthesis.
Functions.VLDL - KIVER,
ENDOGENOUS
TRIGLYCEROL FROM LIVER TO PERIPHERAL TISSUE
IDL-
LIVER, ALSO IN TRANSPORTATION
LDL-
PLASMA TRANSPORT LIVER TO PERIPHERAL TISSUSE(cholesterol)
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