The patient has extensive burns of body. Biochemical examination revealed some amount of total protein in the blood. What result will have this patient?
what is it hyperammonemia? when there is hyperammonemia? Inc^ NH3 in blood Metabolic fate of ammonia. Formation of urea, amination of ketoacid, Glutamate to glutamine, ketogluterate to glutamate Transport of ammonia. NH3+Glutamate -> glutamine -> glutamate +NH3--->urea cycle (tissue blood liver) Reactions of urea cycle. Significance of urea cycle. Dec^ NH3 and make it safe for excretion Regulation of urea cycle . Carbonyl phosphate syanthesis-> rate controling enzyme Metabolic inborn errors of urea cycle 6 enzymes of the cycle CPS1, NAGS, OTC, AS, ASL, AG
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