The patient is 33 years old. Periodically he turns to the doctor with complaints of acute abdominal pain, convulsions and visual disturbances. His relatives have similar symptoms. Urine color is red. The diagnosis is acute intermittent porphyria.


What cause pathologyDeficiency of Enzyme uxoporpyrinogen synthase

Explain the symptoms.

Where heme synthesis First liver after heme synthesis

Substrates for heme Succinyl CoA +glycine

Regulation of heme synthesis Uxoporpyrinogen synthase and ferrochelate



What enzyme defect is observed in acute intermittent porphyria?

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