The sulphonation of toluene is used to produce saccharin. Saccharin is 500 times sweeter than sugar, but it is not metabolized in the body. Sulphonation reactions are type
what is it hyperammonemia? when there is hyperammonemia? Inc^ NH3 in blood Metabolic fate of ammonia. Formation of urea, amination of ketoacid, Glutamate to glutamine, ketogluterate to glutamate Transport of ammonia. NH3+Glutamate -> glutamine -> glutamate +NH3--->urea cycle (tissue blood liver) Reactions of urea cycle. Significance of urea cycle. Dec^ NH3 and make it safe for excretion Regulation of urea cycle . Carbonyl phosphate syanthesis-> rate controling enzyme Metabolic inborn errors of urea cycle 6 enzymes of the cycle CPS1, NAGS, OTC, AS, ASL, AG
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